BOTOX is a therapeutic agent derived from the bacterium, Clostridium Botulinum; Also known as Botulinum Toxin Type A. The brand, BOTOX, is produced in controlled laboratory conditions and given in extremely small therapeutic doses originally for the treatment of blepharospasm (eye spasm) and strabismus (misalignment of the eye). BOTOX Purified Neurotoxin Complex is a vacuum-dried form of purified botulinum toxin type A. and is being investigated for several conditions associated with overactive muscle activity.
BOTOX comes in a vial containing 100u (units) of freeze-dried product. The vials are stored in the office at -5º F until the BOTOX is usually reconstituted with usually either 2 to 4cc of normal saline. At 2cc reconstitution the dose is 50u per cc or 5u per 0.1cc. At 4cc the dose is 25u per cc or 2.5u per 0.1cc. The results are reportedly best if used within 4 hours of reconstitution.
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